Top 10 Causes of Leg Pain and Swelling You Shouldn’t Ignore

Close up of woman holding her leg due to leg swelling and pain in Portland, OR

Leg pain and swelling can range from mild discomfort to signs of a serious medical issue. While occasional soreness after exercise may not be alarming, persistent or worsening symptoms deserve attention. Here are ten possible causes you shouldn’t ignore.

At Inovia Vein Specialty Centers, our expert vein surgeons provide comprehensive diagnosis and treatment for conditions that cause leg pain and swelling, such as varicose veins and chronic venous insufficiency. Founded in Bend, Oregon, Inovia Vein has grown to become the Pacific Northwest’s largest vein-focused practice, offering minimally invasive, office-based procedures that make high-quality vein care affordable and accessible across Oregon and Southwest Washington.

1. Varicose Veins

Bulging, twisted veins can develop when blood pools in the legs due to weakened valves. Varicose veins often cause aching, heaviness, and swelling, especially after standing for long periods.

2. Chronic Venous Insufficiency (CVI)

This is when veins struggle to return blood to the heart, leading to fluid buildup, leg pain, and skin changes. Left untreated, CVI can result in ulcers or infections.

3. Deep Vein Thrombosis (DVT)

A blood clot deep within a vein, often in the calf or thigh, can cause sudden swelling, pain, and warmth. DVT is a serious emergency, as clots can move into the lungs, leading to a pulmonary embolism.

4. Lymphedema

When lymphatic fluid accumulates in the tissues, it causes persistent swelling and a heavy sensation in the legs. It may result from surgery, radiation, or certain infections.

5. Injury or Overuse

Strains, sprains, or muscle tears can lead to swelling and pain that worsens with movement. Rest and ice usually help, but ongoing pain may indicate a more serious issue.

6. Infections

Cellulitis and other skin infections can cause redness, tenderness, and swelling. Medical treatment is essential to prevent complications.

7. Heart Failure

When the heart cannot pump blood efficiently, fluid may back up into the legs, causing swelling and fatigue.

8. Kidney Disease

Hindered kidney function can result in fluid retention, often noticeable as swelling in the legs and ankles.

9. Obesity

Excess weight places strain on veins and joints, increasing the risk of circulation issues and chronic leg pain.

10. Prolonged Sitting or Standing

Remaining in one position for too long can cause fluid to accumulate, leading to temporary swelling in the legs.

Get Answers to Leg Pain and Swelling in Portland, OR

If your leg pain or swelling is sudden, severe, or persistent, seek medical evaluation. Call us today at 800-834-6362 to schedule a consultation. Early diagnosis and treatment can help stop complications and restore healthy circulation.

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